Weikang Tao Selected Research

EBI-1051

1/2018

Discovery of EBI-1051: A novel and orally efficacious MEK inhibitor with benzofuran scaffold.

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Weikang Tao Research Topics

Disease

19	Neoplasms (Cancer) 04/2022 - 11/2005
3	Inflammation (Inflammations) 10/2021 - 03/2011
2	Psoriasis (Pustulosis Palmaris et Plantaris) 01/2022 - 01/2021
2	Colorectal Neoplasms (Colorectal Cancer) 10/2021 - 01/2016
2	Breast Neoplasms (Breast Cancer) 01/2021 - 12/2017
2	Thrombocytopenia (Thrombopenia) 11/2019 - 03/2011
2	Melanoma (Melanoma, Malignant) 01/2018 - 02/2016
1	Osteoarthritis 07/2022
1	Arthralgia (Joint Pain) 07/2022
1	Autoimmune Diseases (Autoimmune Disease) 01/2022
1	Bites and Stings (Sting) 01/2022
1	Inflammatory Bowel Diseases (Inflammatory Bowel Disease) 01/2022
1	Neoplasm Metastasis (Metastasis) 01/2021
1	Pain (Aches) 11/2020
1	Respiratory Insufficiency (Respiratory Failure) 11/2020
1	Hemorrhage 11/2019
1	Thrombosis (Thrombus) 11/2019
1	Vascular Diseases (Vascular Disease) 11/2019
1	Hepatocellular Carcinoma (Hepatoma) 09/2018
1	Chromosomal Instability (Chromosome Stability) 09/2018
1	Acute Pain 12/2017
1	Stomach Neoplasms (Stomach Cancer) 08/2016
1	Carcinoma (Carcinomatosis) 04/2006

Drug/Important Bio-Agent (IBA)

4	CytokinesIBA 01/2022 - 03/2011
4	Pharmaceutical PreparationsIBA 10/2021 - 10/2007
3	AmidesIBA 07/2022 - 04/2006
3	Proteins (Proteins, Gene)FDA Link 01/2018 - 07/2008
2	compound 18IBA 07/2022 - 02/2021
2	LigandsIBA 01/2022 - 11/2019
2	Janus Kinase InhibitorsIBA 01/2022 - 03/2011
2	Interferon Type IIBA 01/2022 - 01/2022
2	Interleukin-6 (Interleukin 6)IBA 01/2022 - 01/2021
2	Janus KinasesIBA 01/2022 - 03/2011
2	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 01/2022 - 01/2018
2	Interleukin-17 (Interleukin 17)IBA 10/2021 - 01/2021
2	Small Interfering RNA (siRNA)IBA 08/2016 - 03/2011
2	EBI-907IBA 02/2016 - 01/2016
2	Phosphotransferases (Kinase)IBA 01/2016 - 03/2011
1	SolutionsIBA 04/2022
1	EnzymesIBA 01/2022
1	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 01/2022
1	TYK2 Kinase (Tyrosine Kinase 2)IBA 01/2022
1	raf KinasesIBA 01/2022
1	Neoplasm Antigens (Tumor Antigens)IBA 01/2022
1	Interleukin-12 (IL 12)IBA 01/2022
1	ADU-S100IBA 01/2022
1	Interleukin-23 (Interleukin 23)IBA 01/2022
1	InterferonsIBA 01/2022
1	cyclic guanosine monophosphate-adenosine monophosphateIBA 01/2022
1	NucleotidesIBA 01/2022
1	compound 17IBA 10/2021
1	Adenosine (Adenocard)FDA LinkGeneric 01/2021
1	Imiquimod (Aldara)FDA LinkGeneric 01/2021
1	Petrolatum (Vaseline)FDA Link 01/2021
1	CarrageenanIBA 11/2020
1	Analgesics (Analgesic Drugs)IBA 11/2020
1	Platelet Aggregation Inhibitors (Antiplatelet Drugs)IBA 11/2019
1	Thromboxane Receptors (Thromboxane Receptor)IBA 11/2019
1	P-SelectinIBA 11/2019
1	Platelet Membrane Glycoprotein IIbIBA 11/2019
1	Immunoconjugates (Immunoconjugate)IBA 01/2019
1	Sorafenib (BAY 43-9006)FDA Link 09/2018
1	EBI-1051IBA 01/2018
1	AZD 6244IBA 01/2018
1	Interleukin-15 (Interleukin 15)IBA 01/2018
1	Opioid Analgesics (Opioids)IBA 12/2017
1	GTP-Binding Proteins (G-Protein)IBA 12/2017
1	pyrotinibIBA 12/2017
1	Tyrosine Kinase InhibitorsIBA 12/2017
1	Cisplatin (Platino)FDA LinkGeneric 08/2016
1	Ubiquitin-Conjugating EnzymesIBA 08/2016
1	Biomarkers (Surrogate Marker)IBA 08/2016
1	VemurafenibIBA 01/2016
1	Dexamethasone (Maxidex)FDA LinkGeneric 03/2011
1	EtoricoxibIBA 03/2011
1	TOR Serine-Threonine KinasesIBA 03/2011
1	Tacrolimus (Prograf)FDA LinkGeneric 03/2011
1	compound 30IBA 07/2008
1	Cytotoxins (Cytolysins)IBA 07/2008
1	PyrrolesIBA 07/2008
1	taxaneIBA 07/2008
1	KinesinsIBA 07/2008
1	AminesIBA 05/2007
1	Urea (Carbamide)FDA LinkGeneric 04/2006
1	pyrrolineIBA 04/2006
1	DNA (Deoxyribonucleic Acid)IBA 11/2005

Therapy/Procedure

7	Therapeutics 07/2022 - 11/2005
2	Immunotherapy 02/2021 - 01/2018
1	Drug Therapy (Chemotherapy) 11/2005